Effect of Stem Cell Treatment on Blood Cancer Patients

Effect of Stem Cell Treatment on Blood Cancer Patients Stephen T. Smith II Abstract Stem cell transplantation, which most of the time is alluded to as peripheral blood, bone marrow, and umbilical cord transplant, is a system that replaces undesirable blood-shaping cells with solid normal cells. Stem cell transplantation permits specialists to give high substantial measurements of chemotherapy or radiation treatment to build the possibility of disposing of blood cancer growth in the marrow and after that reestablishing ordinary cell generation.   As researchers continue to improve with stem cell transplantation, the possibility for more patients to receive this treatment for Leukemia lymphoma, myeloma and Hodgkins disease could increases. In spite of the fact that stem cell transplants can help many patients, notwithstanding giving a few people a possibility for a cure, the choice to have a transplant isnt simple. Noteworthy worthy foundational concerns about stem cell treatment are that by introducing stem cells into an infected body may cause more harm, uncontrolled development, worsen the disease or damage injuries as opposed to treating them.   The transplants have been utilized to cure a large number of individuals with generally savage diseases. Still, the conceivable dangers and confusions can debilitate life, as well. The normal dangers and advantages must be weighed painstakingly before considering a transplant.   The possible risks and complications can be life threatening. Introduction Blood or bone marrow cancer in known as leukemia. There are diverse sorts of leukemia, however, they all begin when something turns out badly with blood-developing cells in bone marrow, the springy tissue inside bones. In leukemia, a portion of the cells are made when these blood-developing cells partition are irregular and they continue isolating wildly, swarming out typical blood and invulnerable cells we have to survive.   Leukemia is normally found in youngsters; more often than it is in grown-ups. Without treatment, leukemia can be deadly. The uplifting news is that doctors have found ways to treat leukemia through stem cells transplants. There are three fundamental types of blood cells, white, red, and platelets, which are created by stem cells. Our bodies require a combination of all three blood cells to keep us alive, for the cells to carry out their employments, every living individual needs a proper balance of each cell in their blood. There are three different types of stem cell transplants, the most well-known type of stem cell transplant is peripheral blood, which is the blood that streams through every living individuals arteries and veins. Bone marrow typically discharges a small amount of peripheral blood stem cells (PBSCs) into the circulation system. To get enough peripheral blood stem cells (PBSCs) for a transplant, the contributor takes a white cell development, for example, granulocyte-state fortifying variable (G-CSF) medication, which builds the number of stem cells by coaxing them out of the marrow and into the blood system. At the point when a patients own particular foundational stems cells are utilized, both granulocyte-state fortifying (G-CSF) and the chemotherapy, which are used to treat cancer usually increase peripheral blood stem cells (PBSCs). In patients who have myeloma and non-Hodgkin lymphoma, the medication plerixafor (Mozobil) can be utilized to assemble their own foundational stem cells. Studies and Treatment Findings Studies have shown that patients with leukemia who have gone through a stem cell transplants using the umbilical cord blood infants are typically helpless against life-threating diseases for no less than a month as their immune system recovers. Umbilical cord blood transplants have been performed in many patients with leukemia and other blood tumors to help the body make fresh recruit cells after its own particular cells, in the body, which have been wrecked by cancer treatment and disease.   The reason why stem cell cord blood transplant are having so much success is because they do not have to be a perfect matched with a patient, unlike bone marrow transplants.   Even though the stem cell cord blood is very versatile and doesnt always need a perfect match only one of three patient and 95% of non-whites who could possibly benefit from a transplant never locate an appropriate match.   Scientists are searching for an approach to expand and speed up the production of white blood cells from the stem cell cord blood with an end goal to fight infections. In any case, stem cell cord blood of newborns contains just around one-tenth of the undeveloped cells found in bone marrow, and this is the reason cord blood transplants, takes such a great amount of time longer to engraft. The reason why stem cell cord blood transplant are having so much success is because they do not have to be a perfect matched with a patient, unlike bone marrow transplants.   Even though the stem cell cord blood is very versatile and doesnt always need a perfect match only one of three patient and 95% of non-whites who could possibly benefit from a transplant never locate an appropriate match. A European Group for Blood and Marrow Transplantation conducted a study of 513 patients with chronic myelomonocytic leukaemia (CMML), and treated them with allogeneic stem cell transplantation (allo-SCT) the two are usually reported together.   The results were complete remission of the disease in 122 patients, 344 did not have any remission, and 47 the results were unknown. The study results determined that allogeneic stem cell transplantation (allo-SCT) should continue to be a curative treatment option for patients with chronic myelomonocytic leukaemia CMML and should be performed preferably early after diagnosis or after establishing the best possible remission status. An individual case study about a 52-yearà ¢Ã¢â€š ¬Ã¢â‚¬Ëœold woman with erythematous skin nodules on her trunk, arms, face, also with bilateral pleural effusion and hepatosplenomegaly who was treated at a Turkish hospital was reported in October 2012. Doctors found Tà ¢Ã¢â€š ¬Ã¢â‚¬Ëœcell acute lymphoblastic leukemia were consistent with precursors in her skin and bone marrow from the biopsy. The woman was started on induction chemotherapy, and remission was achieved. However, in December of 2013 the womans bone marrow examination was clean, but skin lesions started to reappeared.   In January of 2014 the disease reappeared, so doctors started radiation treatment.   The radiation treatment caused the skin lesions progress, but relapse was evident in the bone marrow. In March of 2014 a chemotherapy regimen was started in response to the continued progression of the nodular skin lesions. The chemo treatment was unsuccessful, so May of 2014 the patient was treated with a highà ¢Ã¢ ‚ ¬Ã¢â‚¬Ëœdose of cytosine arabinoside.   The doctors finally decided to try allogeneic bone marrow transplantation, but a donor match could not be identified.  Ã‚   The woman was sent to Istanbul were she underwent un-manipulated peripheral blood stem cell transplant.   The transplant was preform without any extreme difficulties.   The womans body reacted positively to the stem cell treatment the leukemia stay in remission and the nodular skin lesions start to relapse. Conclusion Stem cell research has proven to have success for treatment in leukemia patients, but researcher still have their challenges with stem cells and controlling them, so that they will form the desired type of tissue without causing cancer.  Ã‚   Cancer patients should beware of con artist and pseudoscientific claims, there is a physician in China who runs a clinic where he injects stem cells derived from olfactory sheath cells taken from aborted fetuses into the spines of those suffering from spinal cord injury or motor nerve cell disease.   He claims that this treatment has amazing results curing his patients for their injuries.   His clinic has persuaded many desperate people from around the world, to pay a fee of $20,000 plus all related expenses.   His clinic has all the red flags of not applying basics of the scientific method.   This physician failed to conduct even the most basic observational controls in assessing his treatments. There is no hypothesis to explain his o bservations, no objective tests of function, no imaging or other anatomical or physiological testing to see what has happened to the patients during the experiment and no analyzed data of patients. Most patients accomplish a reduction (a nonappearance of signs and side effects) after starting treatment for intense myeloid leukemia (AML). Notwithstanding, a few patients have lingering leukemic cells in their marrow even after concentrated treatment. This is alluded to as unmanageable leukemia.   The treatment alternatives may incorporate medications not officially utilized amid the primary course of treatment. Foundational stem cell transplantation might be utilized when a reduction is accomplished, which may bring about a more durable remission. A few patients achieve reduction and afterward have an arrival of leukemia cells in the marrow and a lessening in typical platelets. This is called backslid leukemia. In patients who backslide, the length of the abatement, the patients age and the cytogenetic discoveries in the leukemia cells impact the way to deal with treatment. Drugs like those controlled at first, extraordinary medications or undifferentiated organism transplantation might be utilized to treat the leukemia.

Duckett family Essay

The current trend of journalism organizations to hire â€Å"screaming journalists† like Nancy Grace and others is a disservice to the Fourth Estate and threatens the very notion of a free press. Grace and others of her ilk are not reporters seeking the news for its value to the general public nor are they attempting to inform. These confrontational entertainers are more interested in high ratings and controversary than in the news. Furthermore, their lack of general human compassion is endangering the entire profession. Never is this more clear than in the case of the family of Melinda Duckett vs. CNN and Nancy Grace. In September, 2006, Melinda Duckett’s two-year-old son was reported missing and Duckett agreed to appeared on Grace’s show in an effort to promote the manhunt for her missing child. Grace was belligerent and in the woman’s face, screaming at her because she would not discuss her whereabouts when the child disappeared and accusing the woman of having something to do with her child’s disappearance. (Smoking Gun, 2006). Duckett’s son has still not been found, but a day after the interview with Grace, the woman shot and killed herself with a shotgun. In the days following Duckett’s death, Grace not only aired the original interview berating the distraught woman, but she went on the nightly news herself, defending her interviewing techniques. â€Å"Former prosecutor turned talk show host Nancy Grace is unapologetic about her aggressive approach to a mother who committed suicide after an interview about the woman’s missing son,† ABC News reported (â€Å"Nancy Grace says ‘Guilt’). Grace showed no human compassion for the mother in the interview or in the days after her death. Drawing on her history as a criminal prosecutor, Grace attacked in a manner more appropriate for a courtroom than a newsroom. That is not to say that reporters should not ask tough questions, but they should not browbeat an interviewee and speak over them as is reported Grace did. Reporters have a responsibility to seek out the news not make it. In her attacks on Melinda Duckett, Nancy Grace went beyond the level and stepped back into her prosecutorial role, attempting to find the criminal. â€Å"†How is that questioning doing anything but making a person in a desperate situation feeling even more desperate? † said Hub Brown, a professor at Syracuse University’s Newhouse School of Communications. â€Å" (ABC News) Grace defended her unrelenting questioning as a serach for truth and said police later agreed with her that Melinda Duckett is a suspect in her son’s disappearance. What police actually said was that in a child disappearance, the parents are always the initial suspect. Almost a year later, Duckett’s son has still not been found. What has happened, however, is that Grace has put all legitimate journalists in danger of having their rights revoked due to her drive for ratings. In November, 2006, the parents of Melinda Duckett filed a lawsuit against Grace, CNN and Duckett’s estranged husband who helped arrange the Grace interview (Smoking Gun). And, in June, 2007, a Florida court ruled that the case had merit and would be tried in federal court because the participants reside in multiple jurisdictions (â€Å"Ruling in†¦Ã¢â‚¬ ). By bringing this kind of unwanted spectacle to the media, Grace is causing a chilling effect that will lead to fewer people wanting to cooperate with the media and could ultimately lead to a restriction in the rights of journalists. Her lack of basic human compassion is more relevant than whether Melinda Duckett killed or abducted her own son. The role of the media is not to determine the truth, but to report that truth after it has been exhibited by others. While some investigative journalists might argue this point, the reality is that even investigative journalists do not draw their own conclusions about the news. They search for facts and report them. Nancy Grace took facts not in evidence and applied them to the Duckett case, making herself judge, jury and prosecutor of Melinda Duckett without giving Duckett the benefit of a defense attorney. Grace, however, insists her line of questioning was reasonable. â€Å"In an exclusive interview with â€Å"Good Morning America† today, Grace said that she takes no responsibility for Duckett’s suicide. â€Å"If anything, I would suggest that guilt made her commit suicide,† Grace told ABC News’ Chris Cuomo. â€Å"To suggest that a 15 or 20 minute interview can cause someone to commit suicide is focusing on the wrong thing,† she said. â€Å" (ABC NEWS) Grace’s attitude in the wake of Duckett’s suicide is another black eye for the face of journalism. Her unapologetic accusations against the dead woman seemed to indicate that she believes her questioning was appropriate even if it did contribute to Duckett’s death. Her claim that â€Å"even the police agree with me† (ABC News), does little to redeem Grace in the eyes of the general public. Instead, she is seen as so concerned about her ratings that she would put them above human safety. That attitude seems to be in evidence on her webpage. Grace actually advertises for crime victims to call her show and become part of the entertainment value of the news (CNN. com) Though she places her calls for tips in the framework of helping crime victims seek justice, her show advocates her â€Å"Cross Exam† and her prosecutorial drive to find the answers to crime. If Ms. Grace believed that rooting out crime was her calling, she should not have left the prosecutors office for the media. Her style of â€Å"journalism† is an insult to those who attempt to keep the Fourth Estate free of bias and predetermined opinions. Instead, based on her experience, Grace makes judgments calls about people’s guilt as she did with Melinda Duckett and â€Å"reports† the news based on her interpretation of events. She had an exclusive interview with the mother of a missing child, a child police still presume to be alive. Instead of carefully crafter questions designed to help authorities and the general public find the missing boy, Grace decided that badgering Melinda Duckett would mean better ratings. For the sake of the industry, one can only hope that the Duckett family attorneys cannot prove that greed and not news was Grace’s motivation. If they prove that she sought ratings over the truth and therefore did contribute to the death of Melinda Duckett, the chilling effect on all media will be extreme. Her unreasonably harsh questioning methods place all media attempts to get to the truth in danger and violates the most basic tenet of the Fourth Estate: to inform. Nancy Grace has no intention to inform the general public of anything the day she interviewed Melinda Duckett except for her own conviction that Duckett was responsible for her son’s disappearance. This kind of action has no role in journalism, but belongs in editorial and opinion pages, not disguised as news. WORKS CITED ABCNews. com. Nancy Grace says ‘Guilt’ Likely Made Mother Commit Suicide† , June 24, 2007. Nancy Grace Homepage. http://www. cnn. com/CNN/Programs/nancy. grace/, June 24, 2007. â€Å"Ruling Made in Duckett-Grace Case† , June 24, 2007. The Smoking Gun, â€Å"Nancy Grace Sued for Wrongful Death† , June 24, 2007.

The Good, the Bad and Samples of Long Essay

The Good, the Bad and Samples of Long Essay This type of a topic calls for lots of research on the discipline. The essay ought to be such that it may reflect the true situation by means of a spectrum of thoughts, in a way that may continue to keep the interest and facts on the exact same boat. Learn the decision whether to earn n any prosperous essay. Don't neglect to paraphrase your thesis statement and earn prognosis for the future. Type two diabetes mellitus is the most frequently encountered sort of diabetes that affects the way the body metabolizes. Once a patient is a powerful self-manager, he or she is able to get the job done well even without the existence of the nurse. The lifespan of the individual is an issue they need to deal with too. This approach may also be employed by the nurse to educate Steve on blood glucose levels. 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The Issue Of Gay Marriage - 1191 Words

Christina Abreu Professor Peter Lamar Introduction to Classics in Philosophy 6 November 2014 Gay Marriage Thomas Jefferson wrote about â€Å"unalienable rights† in The Declaration of Independence. What he meant was there are rights that are given to us as human beings and cannot be taken away by the government. â€Å"Life, Liberty and the Pursuit of Happiness† are among those rights that are being suppressed against same sex couples. Their right to pursue happiness with their significant other is taken from them by the state. Psychologically and medically married couples are healthier in general because they have someone to share their good days and bad days with as well as someone to take care of when they are sick. However some marriages are not so healthy where one of the partners is abusive whether emotionally or physically and it usually occurs in heterosexual relationships. Orphaned children and children in the foster system also benefit from the union of gay couples because since they can’t have their own children they often look to adoption when starting their own families. Because homosexuals are denied the right of marriage to their loved ones they take marriage more seriously than most heterosexuals who take their right for granted. While the Constitution never specifically stated a need for â€Å"separation of the church and the state† the idea is implied because America is a diverse nation and â€Å"freedom of religion† definitely is in the constitution. â€Å"Freedom of religion†Show MoreRelatedThe Issue Of Gay Marriages1028 Words   |  5 Pages1101-113 September 2, 2015 The Issue Of Gay Marriages Through The Eyes Of Sociologists Gay marriages have been an ongoing event in the United States for many years. It was not until June 26, 2015 when gay marriage was legalized for all states with a five to four ratio. With gay marriage being legalized, there became many controversies in the nation. The most recent controversy was when a Kentucky county clerk was jailed after defying a federal court order to issue marriage licenses to a same-sex coupleRead MoreGay Marriage and Its Issues1260 Words   |  6 PagesGay Marriage and its Issues Gay marriage has been an issue for a very long time and since some states are legalizing it, many worry that it would soon be added as an amendment. The topic of gay marriage brings up religious, legal, and many other issues. In Whats wrong with Gay Marriage? by Katha Pollitt, the author supports gay marriage and wants it legalized. She states that there is no problem with gay marriage and its all a matter of separating the church and state. But in â€Å"Gay ‘Marriage’:Read MoreIssue of Gay Marriage1216 Words   |  5 PagesThe Issue of Gay Marriage Summary This essay debates the issue of same sex marriage in the United States. It considers the pros and cons and examines the constitutional issues involved. Introduction Two strangers become friends and later fall in love. They tell their friends and family that they have each found their soul mate and they intend to get married as soon as possible. There is only one issue preventing them from getting married, not financial issues, and there are no love trianglesRead MoreThe Issue of Gay Marriages918 Words   |  4 PagesGay marriage has come to be a pressing topic in the contemporary society as more and more individuals get actively involved in discussing it. Individuals who oppose same-sex marriage are typically inclined to bring on a deontological argument or to say that legalizing the act might bring on other issues. In contrast, people who support gay marriages focus on matters related to human rights and justice. 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Although the solution to this public crises is to let them have their rights, many opposing people classify their arguments as correct or valid. However clear the answer may be, it has yet to be confirmed by all the states in America. Some major factors that lead to this conflict is whether homosexualityRead MoreThe Issue Of Gay Marriage2127 Words   |  9 Pageslonger us as Americans fighting a common enemy such as England, it was now Americans vs Americans. Multiple issues such as gun laws and religion have separated the United States since its creation. Though recently, the main issue that has caused a divide in the American population is the issue of gay marriage. In the past year the most important piece of legislation in favor of gay marriage and equal rights was created, and it all spurred off of a single court case. Obergefell v. Hodges. In orderRead MoreThe Issue Of Gay Marriage3385 Words   |  14 PagesHistory teaches us that marriage has classically been between a man and a woman, but in the recent years, people have begun to challenge that notion. Gay marriage has been one of the most controversial topics of debate lately, dividing our nation into those who support the idea and those who oppose. It seems as though no matter who is as ked, each person’s opinion falls to one side or the other. States have been similarly divided in their treatment of the gay marriage issue. Voters in some states haveRead MoreThe Issue Of Gay Marriage Essay3392 Words   |  14 PagesWell it is 2007, and we are still dealing with the issue of gay marriage being good, and not good for America. Now maybe in 20 years gay marriage will be legal in each state, and this issue will be over. However, I deal in reality. And reality tells me the idea of two men frotting inside a home with children, frankly makes people sick to their stomachs. I prefer women, but I think what two grown people do in their bedrooms is their private moral, and legal business. Just like a straight couple thatRead MoreThe Issue Of Gay Marriage2016 Words   |  9 Pagesthem. Christians for example do not believe in gay marriage. It is not part of their truth and most likely never will be. This is because they believe in the bible, and a god (higher power) w hich tells them that gay marriage is wrong. They use this information to decide what their truth is and how they will live out their lives. On the flip side of this there are many people who were raised, or influenced by people who are completely fine with gay marriage therefore those people whom they influence (the